In an animal research "first," disease-causing bacteria have been found to gain strength from interaction with single-celled organisms called protozoa that are naturally present inside animals. This finding suggests that the protozoa in animals’ digestive tracts may be a place where dangerous bacteria can lurk and develop.

In studies at the Agricultural Research Service National Animal Disease Center in Ames, Iowa, veterinary medical officer Steven Carlson and microbiologist Mark Rasmussen discovered that an antibiotic-resistant strain of Salmonella becomes especially virulent when tucked inside protozoa in the rumen, or first stomach, of cattle.

The strengthening of disease-causing bacteria as they occupy protozoa is a process that’s been seen with free-living protozoa in places such as water-cooling towers and ponds, according to Rasmussen. This strengthening process was discovered when it was linked to an infamous and deadly 1976 outbreak of Legionnaires’ disease. But the recent study marks the first time the process has been seen inside an animal, Rasmussen added.

Carlson and Rasmussen also found a way to combat DT104 by using a cleansing process, called "defaunation," which rids the rumen of protozoa.